Protein:LILRB1 |
Protein Summary |
 Gene summary |
| Gene name: LILRB1 | ASpdb.0 ID: 10859 | Gene | Gene symbol | LILRB1 | Gene ID | 10859 |
| Gene name | leukocyte immunoglobulin like receptor B1 |
| Synonyms | CD85J|ILT-2|ILT2|LIR-1|LIR1|MIR-7|MIR7|PIR-B|PIRB |
| Cytomap | 19q13.42 |
| Type of gene | protein-coding |
| Description | leukocyte immunoglobulin-like receptor subfamily B member 1CD85 antigen-like family member JIg-like transcript 2immunoglobulin heavy chain variable regionleucocyte Ig-like receptor B1leukocyte immunoglobulin-like receptor, subfamily B (with TM and IT |
| Modification date | 20240411 |
| UniProtAcc | Q8NHL6 |
| Gene ontology of this gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Gene | LILRB1 | GO:0001540 | amyloid-beta binding | 24052308 |
| Gene | LILRB1 | GO:0001915 | negative regulation of T cell mediated cytotoxicity | 21213105 |
| Gene | LILRB1 | GO:0002230 | positive regulation of defense response to virus by host | 18398485 |
| Gene | LILRB1 | GO:0002309 | T cell proliferation involved in immune response | 18094328 |
| Gene | LILRB1 | GO:0002719 | negative regulation of cytokine production involved in immune response | 18094328 |
| Gene | LILRB1 | GO:0002774 | Fc receptor mediated inhibitory signaling pathway | 9842885 |
| Gene | LILRB1 | GO:0005737 | cytoplasm | 15585844 |
| Gene | LILRB1 | GO:0007165 | signal transduction | 18802077 |
| Gene | LILRB1 | GO:0009615 | response to virus | 9285411|17869268|18094328 |
| Gene | LILRB1 | GO:0009897 | external side of plasma membrane | 9285411|15585844|17869268|18094328|18684926|21233315|21551166 |
| Gene | LILRB1 | GO:0010628 | positive regulation of gene expression | 18094328 |
| Gene | LILRB1 | GO:0014063 | negative regulation of serotonin secretion | 11907092 |
| Gene | LILRB1 | GO:0023025 | MHC class Ib protein complex binding | 17056715|28636952 |
| Gene | LILRB1 | GO:0023029 | MHC class Ib protein binding | 11169396 |
| Gene | LILRB1 | GO:0030107 | HLA-A specific inhibitory MHC class I receptor activity | 18684926 |
| Gene | LILRB1 | GO:0030109 | HLA-B specific inhibitory MHC class I receptor activity | 11907092 |
| Gene | LILRB1 | GO:0032393 | MHC class I receptor activity | 9285411|9842885|17869268|18094328|18398485|18802077|21213105|21233315 |
| Gene | LILRB1 | GO:0032394 | MHC class Ib receptor activity | 24453251 |
| Gene | LILRB1 | GO:0032688 | negative regulation of interferon-beta production | 21213105 |
| Gene | LILRB1 | GO:0032689 | negative regulation of type II interferon production | 17869268|18684926 |
| Gene | LILRB1 | GO:0032693 | negative regulation of interleukin-10 production | 18094328 |
| Gene | LILRB1 | GO:0032695 | negative regulation of interleukin-12 production | 18094328 |
| Gene | LILRB1 | GO:0032720 | negative regulation of tumor necrosis factor production | 18684926 |
| Gene | LILRB1 | GO:0032729 | positive regulation of type II interferon production | 11907092|15585844 |
| Gene | LILRB1 | GO:0032945 | negative regulation of mononuclear cell proliferation | 21551166 |
| Gene | LILRB1 | GO:0042130 | negative regulation of T cell proliferation | 15585844 |
| Gene | LILRB1 | GO:0042169 | SH2 domain binding | 11907092 |
| Gene | LILRB1 | GO:0042288 | MHC class I protein binding | 9842885|18094328|18802077|21213105 |
| Gene | LILRB1 | GO:0043065 | positive regulation of apoptotic process | 21551166 |
| Gene | LILRB1 | GO:0045786 | negative regulation of cell cycle | 21551166 |
| Gene | LILRB1 | GO:0045806 | negative regulation of endocytosis | 18094328 |
| Gene | LILRB1 | GO:0045953 | negative regulation of natural killer cell mediated cytotoxicity | 12874224|18398485 |
| Gene | LILRB1 | GO:0046636 | negative regulation of alpha-beta T cell activation | 21213105 |
| Gene | LILRB1 | GO:0051607 | defense response to virus | 15585844 |
| Gene | LILRB1 | GO:0051926 | negative regulation of calcium ion transport | 9842885 |
| Gene | LILRB1 | GO:0060907 | positive regulation of macrophage cytokine production | 19304799 |
| Gene | LILRB1 | GO:0071635 | negative regulation of transforming growth factor beta production | 18094328 |
| Gene | LILRB1 | GO:2000669 | negative regulation of dendritic cell apoptotic process | 18094328 |
| Gene | LILRB1 | GO:2001186 | negative regulation of CD8-positive, alpha-beta T cell activation | 21213105 |
| Gene | LILRB1 | GO:2001189 | negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell | 18094328 |
| Gene | LILRB1 | GO:2001193 | positive regulation of gamma-delta T cell activation involved in immune response | 21233315 |
| Gene | LILRB1 | GO:2001205 | negative regulation of osteoclast development | 18802077 |
AS Summary |
| Information of the canonical protein with experimentally identified structure from PDB (2023). |
| UniProt Acc | File name | PDB ID | Method | Resolution | Chain | Start | End |
| Q8NHL6-1 | Q8NHL6-1_6zdx_B.pdb | 6ZDX | X-ray | 3.0 | B | 25 | 420 |
| ASpdb's canonical and alternatively spliced isoform information. |
| accession_id | gene_name | canonical_id | alternative_id | canonical_length | alternative_length | canonical_start | canonical_end | type | originalSEQ | variationSEQ | alternative_start | alternative_end |
| Q8NHL6 | LILRB1 | Q8NHL6-1 | Q8NHL6-2 | 650 | 651 | 437 | 437 | Substitution | S | SA | 437 | 438 |
| Q8NHL6 | LILRB1 | Q8NHL6-1 | Q8NHL6-3 | 650 | 652 | 437 | 437 | Substitution | S | SA | 437 | 438 |
| Q8NHL6 | LILRB1 | Q8NHL6-1 | Q8NHL6-3 | 650 | 652 | 550 | 550 | Substitution | R | RQ | 551 | 552 |
| Q8NHL6 | LILRB1 | Q8NHL6-1 | Q8NHL6-4 | 650 | 651 | 550 | 550 | Substitution | R | RQ | 550 | 551 |
| Q8NHL6 | LILRB1 | Q8NHL6-1 | Q8NHL6-5 | 650 | 456 | 437 | 437 | Substitution | S | SA | 437 | 438 |
| Q8NHL6 | LILRB1 | Q8NHL6-1 | Q8NHL6-5 | 650 | 456 | 455 | 455 | Substitution | L | E | 456 | 456 |
| Q8NHL6 | LILRB1 | Q8NHL6-1 | Q8NHL6-5 | 650 | 456 | 456 | 650 | Deletion | none | none | 456 | 456 |
| Multiple sequence alignment of our canonical and alternatively spliced LILRB1 |
| Matched gene isoform IDs with Ensembl and RefSeq of our canonical and alternative spliced genes of LILRB1 |
| UniProt-id | ENSG | ENST | ENSP |
| Q8NHL6-1 | ENSG00000277807.5 | ENST00000618055.4 | ENSP00000480365.1 |
| Q8NHL6-2 | ENSG00000277807.5 | ENST00000618681.4 | ENSP00000479753.1 |
| Q8NHL6-3 | ENSG00000277807.5 | ENST00000612636.4 | ENSP00000479887.1 |
| Q8NHL6-4 | ENSG00000277807.5 | ENST00000617686.4 | ENSP00000478282.1 |
| UniProt-id | NM ID | NP ID |
| Amino acid sequences of our canonical and alternatively spliced LILRB1 |
| accession_id | Protein sequence |
| Q8NHL6-1 | MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVKKGQFPIPSITW EHAGRYRCYYGSDTAGRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRA IFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAG AQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKE GAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPSSPTTGPTSTSGPEDQPLTPTGSD PQSGLGRHLGVVIGILVAVILLLLLLLLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGLQWRSSPAADAQEENLYAAVKHTQ PEDGVEMDTRSPHDEDPQAVTYAEVKHSRPRREMASPPSPLSGEFLDTKDRQAEEDRQMDTEAAASEAPQDVTYAQLHSLTLRREATEPP |
| Q8NHL6-2 | MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVKKGQFPIPSITW EHAGRYRCYYGSDTAGRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRA IFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAG AQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKE GAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPSSPTTGPTSTSAGPEDQPLTPTGS DPQSGLGRHLGVVIGILVAVILLLLLLLLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGLQWRSSPAADAQEENLYAAVKHT QPEDGVEMDTRSPHDEDPQAVTYAEVKHSRPRREMASPPSPLSGEFLDTKDRQAEEDRQMDTEAAASEAPQDVTYAQLHSLTLRREATEP |
| Q8NHL6-3 | MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVKKGQFPIPSITW EHAGRYRCYYGSDTAGRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRA IFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAG AQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKE GAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPSSPTTGPTSTSAGPEDQPLTPTGS DPQSGLGRHLGVVIGILVAVILLLLLLLLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGLQWRSSPAADAQEENLYAAVKHT QPEDGVEMDTRQSPHDEDPQAVTYAEVKHSRPRREMASPPSPLSGEFLDTKDRQAEEDRQMDTEAAASEAPQDVTYAQLHSLTLRREATE |
| Q8NHL6-4 | MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVKKGQFPIPSITW EHAGRYRCYYGSDTAGRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRA IFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAG AQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKE GAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPSSPTTGPTSTSGPEDQPLTPTGSD PQSGLGRHLGVVIGILVAVILLLLLLLLLFLILRHRRQGKHWTSTQRKADFQHPAGAVGPEPTDRGLQWRSSPAADAQEENLYAAVKHTQ PEDGVEMDTRQSPHDEDPQAVTYAEVKHSRPRREMASPPSPLSGEFLDTKDRQAEEDRQMDTEAAASEAPQDVTYAQLHSLTLRREATEP |
| Q8NHL6-5 | MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRLYREKKTALWITRIPQELVKKGQFPIPSITW EHAGRYRCYYGSDTAGRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRA IFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAG AQPQAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKE GAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPSSPTTGPTSTSAGPEDQPLTPTGS |
Protein Functional Features |
| Main function of this protein. (from UniProt) |
| LILRB1 (go to UniProt):Q8NHL6 |
| Retention analysis result of protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - Retained protein feature among the 13 regional features. |
| Accession_id | Subsection | Start | End | Funcitonal feature | Splicing information |
| Q8NHL6 | Topological domain | 24 | 461 | Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255 | Type=Substitution;Start=437;End=437 |
| Q8NHL6 | Topological domain | 24 | 461 | Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255 | Type=Substitution;Start=437;End=437 |
| Q8NHL6 | Topological domain | 24 | 461 | Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255 | Type=Substitution;Start=437;End=437 |
| Q8NHL6 | Topological domain | 24 | 461 | Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255 | Type=Substitution;Start=455;End=455 |
| Q8NHL6 | Topological domain | 24 | 461 | Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255 | Type=Deletion;Start=456;End=650 |
| Q8NHL6 | Transmembrane | 462 | 482 | Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255 | Type=Deletion;Start=456;End=650 |
| Q8NHL6 | Topological domain | 483 | 650 | Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255 | Type=Substitution;Start=550;End=550 |
| Q8NHL6 | Topological domain | 483 | 650 | Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255 | Type=Substitution;Start=550;End=550 |
| Q8NHL6 | Topological domain | 483 | 650 | Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255 | Type=Deletion;Start=456;End=650 |
| Q8NHL6 | Region | 415 | 451 | Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite | Type=Substitution;Start=437;End=437 |
| Q8NHL6 | Region | 415 | 451 | Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite | Type=Substitution;Start=437;End=437 |
| Q8NHL6 | Region | 415 | 451 | Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite | Type=Substitution;Start=437;End=437 |
| Q8NHL6 | Region | 491 | 524 | Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite | Type=Deletion;Start=456;End=650 |
| Q8NHL6 | Region | 563 | 650 | Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite | Type=Deletion;Start=456;End=650 |
| Q8NHL6 | Motif | 531 | 536 | Note=ITIM motif 1 | Type=Deletion;Start=456;End=650 |
| Q8NHL6 | Motif | 560 | 565 | Note=ITIM motif 2 | Type=Deletion;Start=456;End=650 |
| Q8NHL6 | Motif | 612 | 617 | Note=ITIM motif 3 | Type=Deletion;Start=456;End=650 |
| Q8NHL6 | Motif | 642 | 647 | Note=ITIM motif 4 | Type=Deletion;Start=456;End=650 |
| Q8NHL6 | Compositional bias | 423 | 451 | Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite | Type=Substitution;Start=437;End=437 |
| Q8NHL6 | Compositional bias | 423 | 451 | Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite | Type=Substitution;Start=437;End=437 |
| Q8NHL6 | Compositional bias | 423 | 451 | Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite | Type=Substitution;Start=437;End=437 |
| Q8NHL6 | Compositional bias | 587 | 602 | Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite | Type=Deletion;Start=456;End=650 |
Gene Isoform Structures and Expression Levels for LILRB1 |
| Gene structures of our canonical and alternative spliced genes of LILRB1 * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Expression levels of gene isoforms across GTEx. |
 |
| Expression levels of gene isoforms across TCGA. |
 |
Protein Structures |
| PDB and CIF files of the predicted protein structures * Here we show the 3D structure of the proteins using Mol*. AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Model confidence is shown from the pLDDT values per residue. pLDDT corresponds to the model’s prediction of its score on the local Distance Difference Test. It is a measure of local accuracy (from AlphfaFold website). To color code individual residues, we transformed individual PDB files into CIF format. |
| 3D view using mol* of Q8NHL6-1 |
| 3D view using mol* of Q8NHL6-2 |
| 3D view using mol* of Q8NHL6-3 |
| 3D view using mol* of Q8NHL6-4 |
| 3D view using mol* of Q8NHL6-5 |
pLDDT Score Distribution |
| pLDDT score distribution of the predicted protein structures from AlphaFold2 * AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. |
| pLDDT distribution across the protein length of Q8NHL6-1 |
 |
| pLDDT distribution across the protein length of Q8NHL6-2 |
 |
| pLDDT distribution across the protein length of Q8NHL6-3 |
 |
| pLDDT distribution across the protein length of Q8NHL6-4 |
 |
| pLDDT distribution across the protein length of Q8NHL6-5 |
 |
Ramachandran Plot of Protein Structures |
| Ramachandran plot of the torsional angles - phi (φ)and psi (ψ) - of the residues (amino acids) contained in this protein peptide. |
| Ramachandran plot of Q8NHL6-1 |
 |
| Ramachandran plot of Q8NHL6-3 |
 |
| Ramachandran plot of Q8NHL6-5 |
 |
Potential Active Site Information |
| The potential binding sites of these proteins were identified using SiteMap, a module of the Schrodinger suite. |
| UniProt-id | Site score | Size | D score | Volume | Exposure | Enclosure | Contact | Phobic | Philic | Balance | Don/Acc | Residues |
| Q8NHL6-1 | 1.002 | 148 | 1.027 | 521.36 | 0.617 | 0.691 | 0.881 | 0.535 | 1.007 | 0.532 | 0.91 | 123,124,125,126,127,147,148,149,196,212,213,214,21 5,216,257,258,259,262,263,264,265,266,267,284,290, 291,295,579,580,581 |
| Q8NHL6-2 | 1.029 | 309 | 1.058 | 982.695 | 0.506 | 0.718 | 0.944 | 0.719 | 0.96 | 0.749 | 0.586 | 123,124,125,126,127,146,147,148,149,194,196,212,21 3,214,215,216,218,254,256,257,258,259,262,263,264, 265,266,267,268,269,282,283,284,290,291,295,615,61 6,617,618,619,620,621,623,624 |
| Q8NHL6-3 | 1.021 | 266 | 1.043 | 738.479 | 0.557 | 0.718 | 0.928 | 0.606 | 1.005 | 0.603 | 0.649 | 123,124,125,126,127,128,129,133,146,147,148,149,21 2,213,214,215,216,256,257,258,259,262,263,264,265, 266,267,268,281,282,283,284,285,290,291,295,615,61 6,617,618,619,620,621,622,623,624 |
| Q8NHL6-4 | 1.051 | 261 | 1.093 | 721.672 | 0.548 | 0.722 | 0.935 | 0.917 | 0.859 | 1.067 | 0.844 | 123,124,125,126,127,133,146,147,148,149,212,213,21 4,215,216,256,257,258,259,262,263,264,265,266,267, 268,281,282,283,284,290,291,295,613,615,616,617,61 8,619,620,622 |
| Q8NHL6-5 | 0.996 | 135 | 1.032 | 490.147 | 0.666 | 0.661 | 0.858 | 0.399 | 0.936 | 0.426 | 1.303 | 32,33,35,36,37,38,39,40,114,115,117,152,153,155,15 7,159,160,163,164,165,166,167,169,170,171,172,173, 196,198,200,202,205,206,208 |
Protein Structure and Feature Comparision |
| Protein Structure Comparision Using Template Modeling Scores (TM-score). |
 |
| Protein Structure Comparision Visualization with mol*. between Canonical predicted structure (AF2)(orange) vs Canonical validated structure (PDB)(green) |
| 3D view using mol* of Q8NHL6-1_Q8NHL6-1_6zdx_B.pdb |
| Protein Structure Comparision Visualization with mol*. between Canonical validated structure (PDB)(orange) vs Alternative predicted structure (AF2)(green) |
| 3D view using mol* of Q8NHL6-1_6zdx_B_Q8NHL6-2.pdb |
| 3D view using mol* of Q8NHL6-1_6zdx_B_Q8NHL6-3.pdb |
| 3D view using mol* of Q8NHL6-1_6zdx_B_Q8NHL6-4.pdb |
| 3D view using mol* of Q8NHL6-1_6zdx_B_Q8NHL6-5.pdb |
| Protein Structure Comparision Visualization with mol*. between Canonical predicted structure (AF2)(orange) vs Alternative predicted structure (AF2)(green) |
| 3D view using mol* of Q8NHL6-1_Q8NHL6-2.pdb |
| 3D view using mol* of Q8NHL6-1_Q8NHL6-3.pdb |
| 3D view using mol* of Q8NHL6-1_Q8NHL6-4.pdb |
| 3D view using mol* of Q8NHL6-1_Q8NHL6-5.pdb |
| Protein Feature Comparison of the protein sequendary structures among the protiens. |
| ./stats/secondary_structure/figure/Q8NHL6-1_vs_Q8NHL6-2.png |
 < |
| ./stats/secondary_structure/figure/Q8NHL6-1_vs_Q8NHL6-3.png |
 < |
| ./stats/secondary_structure/figure/Q8NHL6-1_vs_Q8NHL6-4.png |
 < |
| ./stats/secondary_structure/figure/Q8NHL6-1_vs_Q8NHL6-5.png |
 < |
| Protein Feature Comparison of the relative accessible surface area (ASA) among the protiens. |
| ./stats/relative_asa/Q8NHL6-1_vs_Q8NHL6-2.png |
 < |
| ./stats/relative_asa/Q8NHL6-1_vs_Q8NHL6-3.png |
 < |
| ./stats/relative_asa/Q8NHL6-1_vs_Q8NHL6-4.png |
 < |
| ./stats/relative_asa/Q8NHL6-1_vs_Q8NHL6-5.png |
 < |
Protein-Protein Interaction |
| Interactors from UniProt. |
| Accession_id | Subsection | Start | End | Funcitonal feature | Splicing information |
| Interactors from STRING. |
| Gene name | Interactors |
Related Drugs to LILRB1 |
| Drugs targeting this gene/protein. (DrugBank) |
| UniProt accession | Gene name | DrugBank ID | Drug name | Drug group | Actions |
Related Diseases to LILRB1 |
| Previous studies relating to the alternative splicing of LILRB1 and disease information from the MeSH term (PubMed) |
| Gene | PMID | Title | Abstract | MeSH ID | MeSH term |
Clinically important variants in LILRB1 |
| (ClinVar, 04/20/2024) |
| accession_id | uniprot_id | gene_name | Type | Variant | Clinical_significance |
Copyright 2024-PresentThe University of Texas Health Science Center at Houston (UTHealth Houston) Web File Viewing | Emergency Information |